SYNAREL

Drug Name: SYNAREL

SYNAREL DESCRIPTION:
NAFARELIN ACETATE - NASAL SPRAY (naff-uh-RELL-in A-seh-tate)

COMMON SYNAREL BRAND NAME(S):
Synarel

SYNAREL SIDE EFFECTS:
SYNAREL may cause nasal irritation, headache, hot flashes (less common in children) and irritability. These effects should disappear as your body adjusts to the medication. Other effects include vaginal dryness, change in weight, change in sex drive, irregular or lack of menstruation, oily skin, excessive body hair. If any of these effects continue or become bothersome, inform your doctor. Notify your doctor if you experience severe depression or have regular menstrual periods while taking SYNAREL. Menstruation usually stops as a result of SYNAREL. If doses are missed, you may experience some breakthrough bleeding. If you notice other effects not listed above, contact your doctor or pharmacist.

HOW TO USE SYNAREL:
SYNAREL: SYNAREL is a nasal spray. To use this spray, first clear nasal passages by gently blowing your nose. Insert the sprayer into the nose. Sniff as you squeeze the sprayer. Release your grip after you remove the sprayer from your nose. This will prevent mucous from entering the sprayer. Gently sniff two or three more times. If you must use a nasal decongestant while using this medication, wait at least 30 minutes after using this before using the decongestant. For the treatment of endometriosis, SYNAREL is usually started between the second and fourth day of the menstrual period. The spray is usually used twice a day - one spray into one nostril in the morning, and one spray into the other nostril in the evening. Treatment should not last longer than six months. For the treatment of central precocious puberty, the usual dose is 8 sprays per day - two sprays into each nostril in the morning and evening.

SYNAREL USES:
SYNAREL is a hormone which after an initial increase will decrease symptoms of endometriosis such as pelvic pain, menstrual cramps and painful intercourse. SYNAREL is also used in children to treat central precocious puberty.

SYNAREL PRECAUTIONS:
Lab tests may be done periodically while taking this medication to check it's effectiveness. Although menstruation may stop while taking SYNAREL, it should not be considered a reliable form of contraception. Non-hormonal contraceptives such as a condom or diaphragm should be used. Nafarelin must not be used during pregnancy. If you become pregnant or think you may be pregnant, inform your doctor immediately. It is not known if SYNAREL is excreted into breast milk. Consult your doctor before breast-feeding.

SYNAREL OVERDOSE:
If overdose is suspected, contact your local poison control center or emergency room immediately.

MISSED SYNAREL DOSE:
If you miss a dose, use it as soon as remembered; do not use if it is almost time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.

SYNAREL STORAGE:
Store SYNAREL upright at room temperature. Protect it from excessive heat or light.