STREPTASE

Drug Name: STREPTASE

STREPTASE DESCRIPTION:
STREPTOKINASE - INJECTION (strep-toe-KYE-naze)

COMMON STREPTASE BRAND NAME(S):
Kabikinase, Streptase

STREPTASE SIDE EFFECTS:
Nausea, dizziness, low blood pressure or mild fever may occur. It can also cause nerve damage. If any of these effects persist or worsen, notify your doctor promptly. Notify your doctor promptly for any easy bruising, headache, flushing, rapid or abnormal heartbeat or chest pain. An allergic reaction to STREPTASE is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include rash, itching, swelling, dizziness or trouble breathing. Immediately report any signs of bleeding to your doctor. If you notice other effects not listed above, contact your doctor or pharmacist.

HOW TO USE STREPTASE:
STREPTASE: STREPTASE is given by injection by a health care professional. It is important STREPTASE be used as prescribed. It is most effective when administered as soon as possible (within 6 hours after symptoms (e.g., chest pain) appear.

STREPTASE USES:
STREPTASE is an enzyme which works to break up and dissolve blood clots which can block arteries. It is used in the treatment of heart attack or lung blood clots (pulmonary embolism) as well as leg blood clots (deep venous thrombosis-DVT).

STREPTASE PRECAUTIONS:
Tell your doctor if you have any pre-existing bleeding disorders, high blood pressure, endocarditis, recent biopsy or surgery, recent injury or any allergies. Use extra caution to avoid injury and trauma (e.g., carefully brush teeth) while using STREPTASE due to the increased risk of bleeding. STREPTASE should be used only if clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known if STREPTASE appears in breast milk. Consult your doctor before breast-feeding.

STREPTASE DRUG INTERACTIONS:
Tell your doctor of any over-the-counter or prescription medication you may take including any blood thinners, NSAID or aspirin. Drugs that can reverse effects of streptokinase include aminocaproic acid, aprotinin and tranexamic acid. Do not start or stop any medicine without doctor or pharmacist approval.

STREPTASE OVERDOSE:
If overdose is suspected, contact your local poison control center or emergency room immediately.

STREPTASE NOTES:
Laboratory tests will be done frequently while using this medication to monitor its effects and to prevent side effects.

MISSED STREPTASE DOSE:
Continued or repeated doses are usually not necessary for STREPTASE.

STREPTASE STORAGE:
Store in a cool area as directed. Discard any unused medication after the expiration date on the label. Reconstituted solution may be refrigerated between 36 to 46 degrees F (2 to 8 degrees C) if used within 8 hours. Discard unused portion.