PROMETRIUM

Drug Name: PROMETRIUM

PROMETRIUM DESCRIPTION:
PROGESTERONE - ORAL (pro-JESS-ter-own)

PROMETRIUM SIDE EFFECTS:
Stomach upset, cramps, breast tenderness, drowsiness or dizziness may occur. If these effects persist or worsen, notify your doctor promptly. Report promptly: abnormal vaginal bleeding. Unlikely but report promptly: yellowing of the eyes or skin, itching, rash, depression, pain/swelling in the legs. Very unlikely but report promptly: a migraine-type headache. Darkened patches of skin occasionally occur. Use a sunscreen and protective clothing to minimize this effect if it occurs. If you notice other effects not listed above, contact your doctor or pharmacist.

HOW TO USE PROMETRIUM:
PROMETRIUM: PROMETRIUM is taken by mouth. The dosing depends on your medical condition and response to therapy. Follow your doctor's orders carefully. If taking twice daily, the morning dose should be taken 2 hours after breakfast.

PROMETRIUM USES:
Progesterone is a naturally occurring female hormone. This drug is used to treat menstrual problems.

OTHER USES OF PROMETRIUM:
PROMETRIUM may also be used after menopause (change of life), in combination with estrogen, to lower the risk of uterine cancer.

PROMETRIUM PRECAUTIONS:
Tell your doctor your medical history, especially of: allergies (especially to drugs or peanuts), heart disease, kidney disease, liver disease, abnormal vaginal bleeding, cancer, blood clots, strokes, missed abortion, any conditions you had that worsened because of pregnancy or sex steroid use (e.g., norethindrone, progesterone). Limit alcohol consumption as it may increase the side effects of PROMETRIUM. Because PROMETRIUM may cause drowsiness, use caution performing tasks requiring alertness (e.g., driving). PROMETRIUM should not be used during pregnancy. If you become pregnant or think you may be pregnant, inform your doctor immediately. PROMETRIUM is excreted into breast milk. Consult your doctor before breast-feeding.

PROMETRIUM DRUG INTERACTIONS:
Tell your doctor of all nonprescription and prescription medication you may use, especially of drugs that can cause drowsiness such as: sedatives, drugs for sleep, anti- anxiety drugs, anti-seizure medicines, narcotic pain relievers (e.g., codeine), psychiatric medications, muscle relaxants, certain antihistamines (e.g., diphenhydramine). Certain laboratory tests may be altered by PROMETRIUM, such as gonadotropin, progesterone and pregnanediol. Do not start or stop any medicine without doctor or pharmacist approval.

PROMETRIUM OVERDOSE:
If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include nausea, vomiting, sleepiness, and dizziness.

PROMETRIUM NOTES:
Do not share PROMETRIUM with others.

MISSED PROMETRIUM DOSE:
If using 2 capsules daily (200mg) at bedtime and a dose is missed, use an extra dose of 1 capsule (100mg) the following morning then continue with the normal schedule. If using 3 capsules (300mg) daily and a dose is missed, skip the missed dose and resume the normal schedule.

PROMETRIUM STORAGE:
Store at room temperature between 59 and 86 degrees F (15-30 degrees C) away from light and moisture.