NAVELBINE

Drug Name: NAVELBINE

NAVELBINE DESCRIPTION:
VINORELBINE - INJECTION (vye-nor-ELL-bean)

COMMON NAVELBINE BRAND NAME(S):
Navelbine

NAVELBINE SIDE EFFECTS:
Nausea, vomiting, fatigue, constipation, diarrhea, tingling of the feet or hands; mild, reversible hair loss; muscle aches, or irritation at the injection site may occur. If these effects continue or become bothersome, inform your doctor. Notify your doctor if you develop: mouth sores, blood in urine; easy bruising or bleeding; weakness, skin rash, breathing trouble, chest pain. NAVELBINE affects your blood cells reducing your ability to fight off infections. Notify your doctor if you develop any signs of an infection or flu-like symptoms: fever, chills. If you notice other effects not listed above, contact your doctor or pharmacist.

HOW TO USE NAVELBINE:
NAVELBINE: Vinorelbine is injected (only) into a vein over a 6-10 minute period. NAVELBINE must not be injected into the spine. It is usually given once a week. The dose and frequency of use of NAVELBINE will be determined in part by your condition and your response to previous therapy. Follow your doctor's instructions closely and be sure to ask any questions you may have about this therapy.

NAVELBINE WARNING:
If vinorelbine accidentally leaks into surrounding tissue, the skin and/or muscle may be severely damaged. Notify your doctor immediately if you feel pain or irritation at the injection site. Fatalities have occurred when medications similar to vinorelbine were injected into the spine. NAVELBINE is for intravenous (IV) use only. Vinorelbine can cause blood disorders (e.g., granulocytopenia) that can decrease your ability to fight infection. Notify your doctor immediately if you develop signs of infection such as persistent sore throat or fever.

NAVELBINE USES:
NAVELBINE is used to treat cancer.

NAVELBINE PRECAUTIONS:
Tell your doctor if you have: pre-existing liver disease, kidney disease, lung disease, breathing trouble, any allergies. Because it may cause bleeding be careful when brushing or flossing teeth. Avoid people that may have colds or flu or recently received the oral polio vaccine. NAVELBINE must be handled carefully because it can irritate the skin. Vinorelbine is not recommended for use during pregnancy. Consult you doctor before using NAVELBINE. It is not known is NAVELBINE passes into breast milk. Consult your doctor before breast-feeding.

NAVELBINE DRUG INTERACTIONS:
Tell your doctor of any over-the-counter or prescription medication you may take including: cisplatin, mitomycin, other anti-cancer drugs. Do not start or stop any medicine without doctor or pharmacist approval.

NAVELBINE OVERDOSE:
If overdose is suspected, contact your local poison control center or emergency room immediately.

NAVELBINE NOTES:
Laboratory tests and blood tests will be done frequently to monitor the effectiveness of NAVELBINE and to prevent side effects.

MISSED NAVELBINE DOSE:
It is important that each dose be used as directed. If you miss a dose, contact your doctor to establish a new dosing schedule. Do not "double-up" the dose to catch up.

NAVELBINE STORAGE:
Store NAVELBINE in the refrigerator as directed. Do not freeze. Check the expiration date on the label and properly discard of any unused medication after that time.