DISULFIRAM

Drug Name: DISULFIRAM

DISULFIRAM DESCRIPTION:
DISULFIRAM - ORAL (dye-SULL-fur-am)

COMMON DISULFIRAM BRAND NAME(S):
Antabuse

DISULFIRAM SIDE EFFECTS:
DISULFIRAM may cause headache, drowsiness, restlessness, skin rash, acne, garlic-like aftertaste, changes in vision. Inform your doctor if any of these effects persist or worsen. Unlikely to occur but report immediately: tingling hands or feet, fatigue, weakness, loss of appetite, nausea, vomiting, strong stomach pains, dark urine, yellowing of the eyes or skin. If you notice other effects not listed above, contact your doctor or pharmacist.

HOW TO USE DISULFIRAM:
DISULFIRAM: Take DISULFIRAM by mouth, usually one or two tablets daily as directed by your doctor. Tablets can be crushed or mixed with liquid if swallowing is a problem. Do not take DISULFIRAM for at least 12 hours after drinking alcohol. While taking DISULFIRAM, it is extremely important you avoid alcohol in all forms including beer, wine, aftershave lotions, mouthwash, colognes, liquid medications. Read labels carefully, including those of nonprescription products, and ask your pharmacist about the alcohol content if you are uncertain.

DISULFIRAM WARNING:
Disulfiram must never be given to a patient without their permission, nor to a patient under the influence of alcohol.

DISULFIRAM USES:
DISULFIRAM is used to help treat alcoholism. DISULFIRAM is not a cure for alcoholism and must be used in combination with supportive therapy and counseling. DISULFIRAM must never be used without a person's knowledge.

DISULFIRAM PRECAUTIONS:
Tell your doctor your medical history, especially: heart disease, liver or kidney disease, psychiatric problems, diabetes, any allergies (especially to rubber or pesticides). DISULFIRAM causes an intolerance to alcohol. Drinking alcohol while on DISULFIRAM can cause serious effects that can last from 30 minutes to several hours. It produces an unpleasant reaction of flushing, headache, nausea, vomiting, dizziness, sweating, pounding heart (palpitations), blurred vision or weakness when even small amounts of alcohol are ingested. These disulfiram-alcohol reactions can occur up to two weeks after the medication has been stopped. Because disulfiram can cause drowsiness, use caution when driving or engaging in activities requiring alertness. Disulfiram should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known if disulfiram is excreted into breast milk. Consult your doctor before breast-feeding.

DISULFIRAM DRUG INTERACTIONS:
Disulfiram can affect the way your body reacts to other drugs. Tell your doctor about all the medications you use (both prescription and nonprescription), especially: amitriptyline, isoniazid, metronidazole, theophylline, phenytoin, warfarin. Do not start or stop any medicine without doctor or pharmacist approval.

DISULFIRAM OVERDOSE:
If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include unsteadiness, unusual bleeding or bruising, facial flushing, decreased sexual ability, fainting, memory loss, garlic or rotten egg breath, metallic taste, and seizures.

DISULFIRAM NOTES:
Do not allow anyone else to take DISULFIRAM. Laboratory and/or medical tests (e.g., liver function and blood counts) may be performed to monitor your progress.

MISSED DISULFIRAM DOSE:
If you miss a dose, take as soon as remembered if it is within 12 hours of the missed dose. If it is past 12 hours when you remember, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

DISULFIRAM STORAGE:
Store at room temperature between 59 and 86 degrees F (between 15 and 30 degrees C) away from moisture and sunlight. Do not store in the bathroom. Your condition can cause complications in a medical emergency. For information on enrollment call Medic Alert(TM) at 1-800-854-1166. In Canada call 1-800-668-1507.